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Home/The Science

Medicine that speaks the body’s own language.

Anandamide is the cannabinoid your nervous system already makes — the foundation for everything we distribute.

Anandamide · C₂₂H₃₇NO₂ the endocannabinoid your body makes

The endocannabinoid system

Researchers have found the endocannabinoid system helps regulate mood, appetite, sleep, pain and circadian rhythm. It works through a network of receptors — chiefly CB1 in the brain and central nervous system, and CB2 across the immune system.

Plant cannabinoids such as CBD and THC attach to these same receptors. CBD may interact with receptors that influence the sleep–wake cycle, reduce anxiety and pain, and activate serotonin pathways involved in neuropathic pain — which is why dose and ratio, not just “strength”, decide the effect.

CB1 receptors

Concentrated in the brain and nervous system. Influence pain signalling, mood, appetite and motor control — the main site of THC’s activity.

CB2 receptors

Found largely in immune tissue. Linked to inflammation and immune response, relevant to autoimmune and inflammatory conditions.

The entourage effect

Cannabinoids and terpenes appear to work better together than in isolation. Full-spectrum formulations retain 100+ compounds rather than a single isolated molecule.

Why ratio matters

A 1:1 CBD:THC balance behaves very differently from 4:1 or 1:2. Matching ratio to condition is the core of cannabinoid prescribing.

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